Eleonora (Nora) Lad, MD, PhD
Associate Professor of Ophthalmology
Director of Grading, Duke Reading Center
Duke Eye Center
Duke University Medical Center
Iwona Misiuta, PhD, MHA
Clinical Content Manager
Kathryn Schaefer, MSN, RN
Lead Nurse Planner
East Lansing, MI
Upon completion, participants should be able to:
Summarize types of biomarkers of progression and treatment response in macular diseases, with an emphasis on functional endpoints in dry age-related macular degeneration
This activity is intended for ophthalmologists.
Statement of Need
Macular degeneration, often called age-related macular degeneration (AMD), is a leading cause of vision loss in people older than 50 years. The causes of AMD include genetic and lifestyle risk factors such as smoking and poor dietary habits. There are two types of AMD: dry and wet. Dry AMD, which accounts for 80% to 90% of cases, is caused when drusen (damaging, small white or yellowish deposits) form on the retina beneath the macula. Early and intermediate stages of AMD usually start without symptoms. Currently, there is a lack of reliable measures to recognize patients at risk of developing AMD, including patients who are at risk of disease progression to blinding forms. No cure is currently available for this condition, but certain treatments can slow progression, such as nutritional supplements, laser therapy, or photodynamic laser therapy. New clinical trials are attempting to identify early biomarkers to assess disease progression and treatment response in macular diseases, including dry AMD.
This activity was developed by Med-IQ in collaboration with Duke University Health System Department of Clinical Education and Professional Development.
Med-IQ is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Med-IQ designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Instructions to Receive Credit
To receive credit, read the introductory CME material, watch the Webcast, and complete the evaluation, attestation, and post-test, answering at least 70% of the post-test questions correctly.
Initial Release Date: January 9, 2018
Expiration Date: January 8, 2019
Estimated Time to Complete This Activity: 15 minutes
Med-IQ requires any person in a position to control the content of an educational activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines “relevant financial relationships” as those in any amount occurring within the past 12 months, including those of a spouse/life partner, that could create a conflict of interest (COI). Individuals who refuse to disclose will not be permitted to contribute to this CME activity in any way. Med-IQ has policies in place that will identify and resolve COIs prior to this educational activity. Med-IQ also requires faculty to disclose discussions of investigational products or unlabeled/unapproved uses of drugs or devices regulated by the US Food and Drug Administration.
The content of this activity has been peer reviewed and has been approved for compliance. The faculty and contributors have indicated the following financial relationships, which have been resolved through an established COI resolution process, and have stated that these reported relationships will not have any impact on their ability to give an unbiased presentation.
Eleonora (Nora) Lad, MD, PhD
Consulting fees/advisory boards: Apellis Pharmaceuticals, F. Hoffmann-La Roche Ltd., Janssen Pharmaceuticals, Inc., Stealth BioTherapeutics Inc.
Other (clinical studies): Apellis Pharmaceuticals, F. Hoffmann-La Roche Ltd.
The peer reviewers and activity planners have no financial relationships to disclose.
Statement of Evidence-Based Content
Educational activities that assist physicians in carrying out their professional responsibilities more effectively and efficiently are consistent with the ACCME definition of continuing medical education (CME). As an ACCME-accredited provider of CME, it is the policy of Med-IQ to review and ensure that all the content and any recommendations, treatments, and manners of practicing medicine in CME activities are scientifically based, valid, and relevant to the practice of medicine. Med-IQ is responsible for validating the content of the CME activities it provides. Specifically, (1) all recommendations addressing the medical care of patients must be based on evidence that is scientifically sound and recognized as such within the profession; (2) all scientific research referred to, reported, or used in CME in support or justification of a patient care recommendation must conform to generally accepted standards of experimental design, data collection, and analysis.
Med-IQ is not liable for any decision made or action taken in reliance upon the information provided through this activity.
For questions or comments about this activity, please contact Med-IQ.
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