The Arrival of CAR T-Cell Therapy—Exploring the Latest Advances and Impact on Patient Care
Patients should be hospitalized for a minimum of how many days after receiving CAR T-cell therapy?
B.) Patients should remain hospitalized for at least 7 days following CAR T-cell therapy administration.
Click the “Continue” button to learn more about integrating data on CAR T-cell therapy into your treatment planning.
Ref: Neelapu SS, et al. Nat Rev Clin Oncol. 2018;15(1):47-62.
Ahmed Galal, MD
Professor of Medicine
Duke University School of Medicine
Division of Hematologic Malignancies & Cellular Therapy
Duke Cancer Center
Susan Kuhn, MHSc
Manager, Educational Strategy and Content
Lisa R. Rinehart, MS, ELS
Director, Editorial Services
Kathryn Schaefer, MSN, RN, CPHRM
Senior Manager, Accreditation and Compliance
East Lansing, MI
Edward Allan Racela Sison, MD
Missouri City, TX
Upon completion, participants should be able to:
- Describe the principles of CAR T-cell therapy including the mechanism of action and logistics of administration
- Apply the evolving clinical data regarding CAR T-cell therapy in hematologic malignancies to appropriately select patients and understand its future applicability
- Vigilantly monitor for, promptly identify, and appropriately manage toxicities associated with CAR T-cell therapies
This activity is intended for hematology/oncology physicians, nurses, and pharmacists.
Statement of Need
Although CAR T-cell therapies are associated with robust clinical responses, the relative newness of these therapies, complexity of administration, logistics regarding operation, and unique toxicities may make adoption within clinical practice challenging. To effectively incorporate CAR T-cell therapy into the clinic, hematology/oncology clinicians must increase their understanding of CAR T-cell therapy, improve their ability to identify and refer appropriate patients for treatment, stay current on the rapidly emerging clinical data, and promptly identify and manage adverse events. In addition, many multidisciplinary team members are involved in providing care to patients receiving this type of therapy, therefore optimal care coordination is essential. Thus, education regarding integration of CAR T-cell therapies into treatment decision making for patients with relapsed/refractory B-cell malignancies is required to meet the unique educational needs of hematology/oncology care team members.
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Medium/Method of Participation
This CME/CE activity consists of a 1.0-credit online publication. To receive credit, read the introductory CME/CE material, read the publication, and complete the post-survey, evaluation, attestation, and post-test, answering at least 70% of the post-test questions correctly. Pharmacists will have credits uploaded directly to NABP.
Initial Release Date: November 27, 2019
Expiration Date: November 26, 2020
Estimated Time to Complete This Activity: 1 hour
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The content of this activity has been peer reviewed and has been approved for compliance. The faculty and contributors have indicated the following financial relationships, which have been resolved through an established COI resolution process, and have stated that these reported relationships will not have any impact on their ability to give an unbiased presentation.?
Ahmed Galal, MD
Consulting fees/advisory boards: Gilead Sciences, Verastem Oncology
Fees received for promotional/non-CME activities: Celgene Corporation, Gilead Sciences, Incyte Corporation
Susan Kuhn, MHSc
Spouse Ownership interest (stocks/stock options – excluding mutual funds): Illumina, Johnson & Johnson, Viking Therapeutics
Edward Allan Racela Sison, MD
Salary: Covance, Inc.
The peer reviewers and other activity planners have no financial relationships to disclose.
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