Sequencing Treatment for Metastatic Castration-Resistant Prostate Cancer: How to Match Patients to the Right Therapy
E-publication E-publication

Sequencing Treatment for Metastatic Castration-Resistant Prostate Cancer: How to Match Patients to the Right Therapy


Released:
12/15/2016
Expires:
12/14/2017

Maximum Credits:

1.0

E-publication E-publication
Released:
12/15/2016

Expires:
12/14/2017

Maximum Credits:
1.0
E-publication E-publication

Released:
12/15/2016
Expires:
12/14/2017


Maximum Credits:
1.0


Overview: This interactive, audio-enhanced online publication discusses available treatment options for patients with metastatic castration-resistant prostate cancer (mCRPC) in both the first- and second-line settings. Additionally, case studies from a national survey of oncologists and urologists are presented to illuminate common practice challenges. Expert faculty offer their perspectives on the survey results to help readers design effective treatment regimens for patients with mCRPC.

CME Information:

Faculty
Charles J. Ryan, MD
Professor of Clinical Medicine and Urology
Division of Hematology/Oncology
Department of Medicine
Helen Diller Family Comprehensive Cancer Center
University of California, San Francisco
San Francisco, CA
 
Oliver Sartor, MD
Professor, Department of Medicine and Urology
C.E. and Bernadine Laborde Professor of Cancer Research
Tulane University School of Medicine
Medical Director of the Tulane Cancer Center
New Orleans, LA 

Activity Planners
Stephanie Larson, PhD
Clinical Content Manager
Med-IQ
Baltimore, MD
 
Laura Rafferty
Managing Editor
Med-IQ
Baltimore, MD
 
Amy Sison
Director of Continuing Medical Education
Med-IQ
Baltimore, MD

Learning Objectives
Upon completion, participants should be able to:

  • Apply available clinical evidence to individualize optimal first-line treatment for patients with mCRPC
  • Describe clinical evidence and guideline recommendations that guide decisions about appropriate sequencing of therapy beyond first-line therapy for patients with mCRPC

Target Audience
This activity is intended for oncologists.

Series Overview/Statement of Need
Prostate cancer is the most common cancer and the second leading cause of cancer-related death among men in the United States. Of men with newly diagnosed prostate cancer, 15% to 20% have invasive or metastatic disease, which is associated with much lower overall survival. An increase in the number of available therapies for metastatic castration-resistant prostate cancer (mCRPC) has significantly improved overall survival and quality of life for men with this disease. As a result, clinicians face the often complicated task of choosing the most appropriate first-line therapy for a patient. In order to take full advantage of the therapeutic options available for mCRPC, oncologists need to be aware of best practices for using therapies individually or in combination and clinical data on sequencing regimens that can improve overall survival in patients with progressive disease. 

Accreditation/Designation Statements
Med-IQ is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Med-IQ designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Nurse practitioners, physician assistants, and other healthcare professionals who successfully complete the activity will receive a Statement of Participation indicating the maximum credits available.

Medium/Method of Participation
This CME activity consists of a 1.0-credit online publication. To receive credit, read the introductory CME material, read the publication, and complete the post-survey, evaluation, attestation, and post-test, answering at least 70% of the post-test questions correctly.
 
Original Release Date: December 15, 2016
Expiration Date: December 14, 2017
Estimated Time to Complete This Activity: 1 hour

Disclosure Policy
Med-IQ requires any person in a position to control the content of an educational activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines “relevant financial relationships” as those in any amount occurring within the past 12 months, including those of a spouse/life partner, that could create a conflict of interest (COI). Individuals who refuse to disclose will not be permitted to contribute to this CME activity in any way. Med-IQ has policies in place that will identify and resolve COIs prior to this educational activity. Med-IQ also requires faculty to disclose discussions of investigational products or unlabeled/unapproved uses of drugs or devices regulated by the US Food and Drug Administration.

Disclosure Statement
The content of this activity has been peer reviewed and has been approved for compliance. The faculty and contributors have indicated the following financial relationships, which have been resolved through an established COI resolution process, and have stated that these reported relationships will not have any impact on their ability to give an unbiased presentation. 
 
Charles J. Ryan, MD
Royalty: UpToDate, Inc.
Consulting fees/advisory boards: Clovis Oncology
Fees received for promotional/non-CME activities: Astellas Pharma US, Inc., Bayer HealthCare Pharmaceuticals, Janssen Pharmaceuticals, Inc.
 
Oliver Sartor, MD
Consulting fees/advisory boards: Bayer HealthCare Pharmaceuticals, Bellicum Pharmaceuticals, Inc., Bristol-Myers Squibb, Celgene Corporation, Dendreon Corporation, Johnson & Johnson, Medivation, Inc., OncoGenex Pharmaceuticals, Sanofi-aventis U.S. Inc., Tokai Pharmaceuticals
Contracted research: Bayer HealthCare Pharmaceuticals, Endocyte, Innocrin Pharmaceuticals Inc., Johnson & Johnson, Sanofi-aventis U.S. Inc.

The writer, peer reviewers, and activity planners have no financial relationships to disclose.

Statement of Evidence-Based Content
Educational activities that assist physicians in carrying out their professional responsibilities more effectively and efficiently are consistent with the ACCME definition of continuing medical education (CME). As an ACCME-accredited provider of CME, it is the policy of Med-IQ to review and ensure that all the content and any recommendations, treatments, and manners of practicing medicine in CME activities are scientifically based, valid, and relevant to the practice of medicine. Med-IQ is responsible for validating the content of the CME activities it provides. Specifically, (1) all recommendations addressing the medical care of patients must be based on evidence that is scientifically sound and recognized as such within the profession; (2) all scientific research referred to, reported, or used in CME in support or justification of a patient care recommendation must conform to generally accepted standards of experimental design, data collection, and analysis.
 
Med-IQ is not liable for any decision made or action taken in reliance upon the information provided through this activity.

Contact Information
For questions or comments about this activity, please contact Med-IQ. Call (toll-free) 866 858 7434 or e-mail info@med-iq.com.

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Operating System
Microsoft Windows® 8, Windows 7
Mac OS 10.7 (Lion) or newer

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Adobe Flash Player 9 or later
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ADA Statement
Med-IQ fully complies with the legal requirements of the ADA and the rules and regulations thereof. If any participant in this educational activity is in need of accommodations, please contact Med-IQ at 443 543 5200.

Disclaimer
The information provided through this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.

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Acknowledgment of Commercial Support
This activity is supported by an educational grant from Sanofi US.

Copyright
© 2016 Med-IQ®. All rights reserved.

 

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The information provided through this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.

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