Incorporating Immunotherapeutic Advances Into the Clinic: A Case Study in the Treatment of Refractory/Recurrent Advanced or Metastatic Urothelial Cancer
Advanced UC is associated with a poor prognosis, with a median survival of approximately ___ months or less.(1-3)
B.) 15. Advanced UC has an estimated median survival of 15 months or less. Click the “Continue” button to learn more about immunotherapeutic advances in bladder cancer management.
1. Bellmunt J, et al. EJC Suppl. 2016;14:1-20.
2. von der Maase H, et al. J Clin Oncol. 2000;18:3068-77.
3. Oing C, et al.. J Urol. 2016;195:254-63.
Matthew R. Zibelman, MD
Assistant Professor, Department of Hematology/Oncology
Fox Chase Cancer Center
Stephanie Larson, PhD
Clinical Content Manager
Lisa R. Rinehart, MS, ELS
Director, Editorial Services
Kathryn Schaefer, MSN, RN, CPHRM
Senior Manager, Accreditation and Compliance
East Lansing, MI
Upon completion, participants should be able to:
- Apply recent evidence on immune checkpoint inhibitors into treatment decisions for patients with refractory/recurrent advanced or metastatic UC
This activity is intended for oncologists.
Statement of Need
The management of locally advanced or metastatic urothelial carcinoma (UC) has transformed significantly over the past 2 years with the emergence of immune checkpoint inhibitors. The rapidly changing landscape of immunotherapy in the treatment of UC and the use of PD-L1 testing to inform immunotherapy-related decisions highlights the need for oncologists to stay abreast of recently approved immunotherapies to appropriately incorporate these advances into their own clinical practice.
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This CME activity consists of a 0.25-credit online publication. To receive credit, read the introductory CME material, read the publication, and complete the post-survey, evaluation, attestation, and post-test, answering at least 70% of the post-test questions correctly.
Initial Release Date: April 19, 2019
Expiration Date: April 18, 2020
Estimated Time to Complete This Activity: 15 minutes
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Matthew R. Zibelman, MD
Consulting fees/advisory boards: Pfizer, Inc.
Contracted research: Bristol-Myers Squibb, Horizon Pharmaceuticals, Pfizer, Inc.
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