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Med-IQ Express Med-IQ Express

Biomarkers of Diminished Ovarian Reserve and Fertility Testing: What Do Providers Need to Know?


This activity was developed by Med-IQ in collaboration with Duke Health.

Med-IQ      Duke Medicine
 

Released:
7/31/19
Expires:
7/30/20

Maximum Credits:

0.25
By clicking "Continue," you are confirming that you have reviewed the CME information and read, understood, and unconditionally agreed to the Privacy Notice and Terms of Use.

Med-IQ Express Med-IQ Express
By clicking "Continue," you are confirming that you have reviewed the CME information and read, understood, and unconditionally agreed to the Privacy Notice and Terms of Use.
Released:
7/31/19

Expires:
7/30/20

Maximum Credits:
0.25
Med-IQ Express Med-IQ Express
By clicking "Continue," you are confirming that you have reviewed the CME information and read, understood, and unconditionally agreed to the Privacy Notice and Terms of Use.

Released:
7/31/19
Expires:
7/30/20


Maximum Credits:
0.25


Overview: This brief accredited CME publication discusses the gap between current clinical evidence on biomarkers of diminished ovarian reserve (DOR) and the current trend of evaluating natural fertility in women seeking to plan pregnancy and assess the timing of menopause. It also reviews the limitations of ovarian reserve testing and key criteria for selecting patients for evaluation. Additionally, this activity features a short video that provides context for the issues that providers face regarding fertility and pregnancy planning in current practice and considerations for counseling patients.

CME Information:

Faculty
Anne Z. Steiner, MD, MPH
Professor of Obstetrics and Gynecology
Division Chief, Reproductive Endocrinology and Infertility
Duke University School of Medicine
Durham, NC
 
Activity Planners
Erin Grothey, MS
Clinical Content Manager
Med-IQ
Baltimore, MD
 
Laura Rafferty, ELS
Managing Editor
Med-IQ
Baltimore, MD
 
Samantha Gordon
CME Specialist
Med-IQ
Baltimore, MD
 
Kathryn Schaefer, MSN, RN, CPHRM
Senior Manager, Accreditation and Compliance
Med-IQ
East Lansing, MI
 
Writer
Stephanie Wenick, MPhil
Wenick Communications, LLC
Chevy Chase, MD
 
Learning Objectives
Upon completion, participants should be able to:

  • Identify the role of FSH and AMH in assessing reproductive potential in older women with no known infertility based on current evidence

Target Audience
This activity is intended for general obstetricians/gynecologists and primary care physicians who provide testing, care, and/or advice to women of reproductive age.
 
Statement of Need
Women are increasingly looking to become pregnant and grow their families at an older age. As of 2017, approximately one-third of first pregnancies occurred in women aged 30 years or older. To plan their reproductive future, women rely on medical advice from their providers to help understand their possible infertility risk or the timing of the onset of menopause. Although predicting the rate of an individual’s ovarian reserve decline is challenging, ovarian reserve testing has evolved over the years, and advancements have led to greater specificity and convenience. Fertility testing is common in clinics, and at-home kits are readily available. Biomarkers of diminished ovarian reserve (DOR) are useful for assessing fertility, but they have limitations. For instance, they were validated in women who have known infertility and, therefore, are not informative regarding fecundability in women of unknown fertility. Maternal age remains the best indicator of fecundity, but ovarian reserve testing is informative in reproductive-aged women undergoing evaluation for infertility, as biomarkers of ovarian reserve can serve as proxies of oocyte quantity. In contrast to the current trend in fertility testing, the use of biomarkers of DOR to assess the natural fertility of women in the general population is not supported by current evidence.

Collaboration Statement
This activity was developed by Med-IQ in collaboration with Duke Health.
 
Accreditation/Designation Statements
Med-IQ is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
 
Med-IQ designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
 
Medium/Method of Participation
This CME activity consists of a 0.25-credit online publication. To receive credit, read the introductory CME material, read the publication, and complete the evaluation, attestation, and post-test, answering at least 70% of the post-test questions correctly.
 
Initial Release Date: July 31, 2019
Expiration Date: July 30, 2020
Estimated Time to Complete This Activity: 15 minutes

Disclosure Policy
Med-IQ requires any person in a position to control the content of an educational activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines “relevant financial relationships” as those in any amount occurring within the past 12 months, including those of a spouse/life partner, that could create a conflict of interest (COI). Individuals who refuse to disclose will not be permitted to contribute to this CME activity in any way. Med-IQ has policies in place that will identify and resolve COIs prior to this educational activity. Med-IQ also requires faculty to disclose discussions of investigational products or unlabeled/unapproved uses of drugs or devices regulated by the US Food and Drug Administration.

Disclosure Statement
The content of this activity has been peer reviewed and has been approved for compliance. The faculty and contributors have indicated the following financial relationships, which have been resolved through an established COI resolution process, and have stated that these reported relationships will not have any impact on their ability to give an unbiased presentation. 
 
Anne Z. Steiner, MD, MPH, has indicated no real or apparent conflicts.
 
The writer, peer reviewers, and activity planners have no financial relationships to disclose.
 
Statement of Evidence-Based Content
Educational activities that assist physicians in carrying out their professional responsibilities more effectively and efficiently are consistent with the ACCME definition of continuing medical education (CME). As an ACCME-accredited provider of CME, it is the policy of Med-IQ to review and ensure that all the content and any recommendations, treatments, and manners of practicing medicine in CME activities are scientifically based, valid, and relevant to the practice of medicine. Med-IQ is responsible for validating the content of the CME activities it provides. Specifically, (1) all recommendations addressing the medical care of patients must be based on evidence that is scientifically sound and recognized as such within the profession; (2) all scientific research referred to, reported, or used in CME in support or justification of a patient care recommendation must conform to generally accepted standards of experimental design, data collection, and analysis.
 
Med-IQ is not liable for any decision made or action taken in reliance upon the information provided through this activity.
 
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For questions or comments about this activity, please contact Med-IQ. Call (toll-free) 866 858 7434 or email info@med-iq.com.

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The information provided through this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.

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