On the Front Lines of Diagnosis: Preventing Diagnostic Delays in MPS I and Other LSDs
Med-IQ Express Med-IQ Express

On the Front Lines of Diagnosis: Preventing Diagnostic Delays in MPS I and Other LSDs


Released:
12/24/19
Expires:
12/23/20

Maximum Credits:

0.5
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Med-IQ Express Med-IQ Express
By clicking "Continue," you are confirming that you have reviewed the CME information and read, understood, and unconditionally agreed to the Privacy Notice and Terms of Use.
Released:
12/24/19

Expires:
12/23/20

Maximum Credits:
0.5
Med-IQ Express Med-IQ Express
By clicking "Continue," you are confirming that you have reviewed the CME information and read, understood, and unconditionally agreed to the Privacy Notice and Terms of Use.

Released:
12/24/19
Expires:
12/23/20


Maximum Credits:
0.5


Overview: This accredited CME publication highlights the importance of early diagnosis in mucopolysaccharidosis type I (MPS I) and explores the clinical variability of this disorder, including variations of symptomology and disease progression. In addition, this activity features a short video that provides expert commentary from Lorne Clarke, MDCM, FRCPC, FCCMG, on when and how pediatricians and family physicians should screen for MPS I and or refer to a geneticist or metabolic disease specialist.

CME Information:

Faculty
Lorne Clarke, MDCM, FRCPC, FCCMG
Professor, Department of Medical Genetics
Provincial Medical Genetics Program
University of British Columbia
British Columbia, Canada

Activity Planners
Iwona Misiuta, PhD, MHA
Clinical Content Manager
Med-IQ
Baltimore, MD

Rebecca L. Julian, MS, ELS
Senior Manager, Editorial
Med-IQ
Baltimore, MD

Samantha Gordon
CME Specialist
Med-IQ
Baltimore, MD

Kathryn Schaefer, MSN, RN, CPHRM
Senior Manager, Accreditation and Compliance
Med-IQ
East Lansing, MI

Writer
Patrick McCarthy
Bronxville, NY
 
Learning Objective
Upon completion, participants should be able to:

  • Recognize early signs and symptoms of MPS I from birth to adolescence
  • Perform necessary tests to determine whether a patient has MPS I and may require referral to a specialist

Target Audience
This activity is intended for pediatricians, family practice physicians, and general practice physicians.
 
Statement of Need
Lysosomal storage disorders (LSDs) can have devastating effects and cause irreversible damage if patients are not identified and properly managed early in the disease course. Indeed, identifying the LSD MPS I early on is essential for disease prognosis and management. Initiating treatment before irreversible damage has occurred can stabilize the patient and possibly delay disease progression. Pediatricians and family physicians are on the front lines of identifying patients with MPS I. However, most of these clinicians are unaware of MPS I symptoms, even though nearly all patients with MPS I show signs by 6 months of age. Therefore, it is important for pediatricians and family physicians to be educated on MPS I symptom presentations throughout the course of the disease. It is also imperative for these clinicians to know which test to perform or when to refer patients for further testing and disease management.

Providership Statement
Provided by Med-IQ.

Accreditation/Designation Statements
Med-IQ is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Med-IQ designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurse practitioners, physician assistants, and other healthcare professionals who successfully complete the activity will receive a Statement of Participation indicating the maximum credits available.

Medium/Method of Participation
This CME activity consists of a 0.5-credit online publication. To receive credit, read the introductory CME material, read the publication, and complete the post-survey, evaluation, attestation, and post-test, answering at least 70% of the post-test questions correctly.

Initial Release Date: December 24, 2019
Expiration Date: December 23, 2020
Estimated Time to Complete This Activity: 30 minutes 

Disclosure Policy
Med-IQ requires any person in a position to control the content of an educational activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines “relevant financial relationships” as those in any amount occurring within the past 12 months, including those of a spouse/life partner, that could create a conflict of interest (COI). Individuals who refuse to disclose will not be permitted to contribute to this CME activity in any way. Med-IQ has policies in place that will identify and resolve COIs prior to this educational activity. Med-IQ also requires faculty to disclose discussions of investigational products or unlabeled/unapproved uses of drugs or devices regulated by the US Food and Drug Administration.
 
Disclosure Statement
The content of this activity has been peer reviewed and has been approved for compliance. The faculty and contributors have indicated the following financial relationships, which have been resolved through an established COI resolution process, and have stated that these reported relationships will not have any impact on their ability to give an unbiased presentation. 
 
Lorne Clarke, MDCM, FRCPC, FCCMG
Consulting fees/advisory boards: BioMarin, Sanofi Genzyme
Fees received for promotional/non-CME activities: BioMarin, Sanofi Genzyme

The writer, peer reviewers, and activity planners have no financial relationships to disclose.

Statement of Evidence-Based Content
Educational activities that assist physicians in carrying out their professional responsibilities more effectively and efficiently are consistent with the ACCME definition of continuing medical education (CME). As an ACCME-accredited provider of CME, Med-IQ has a policy to review and ensure that all the content and any recommendations, treatments, and manners of practicing medicine in CME activities are scientifically based, valid, and relevant to the practice of medicine. Med-IQ is responsible for validating the content of the CME activities it provides. Specifically, (1) all recommendations addressing the medical care of patients must be based on evidence that is scientifically sound and recognized as such within the profession; (2) all scientific research referred to, reported, or used in CME in support or justification of a patient care recommendation must conform to generally accepted standards of experimental design, data collection, and analysis.
 
Med-IQ is not liable for any decision made or action taken in reliance upon the information provided through this activity.

Contact Information        
For questions or comments about this activity, please contact Med-IQ. Call (toll-free) 866 858 7434 or email info@med-iq.com.          
                      
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Disclaimer
The information provided through this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.

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Acknowledgment of Commercial Support
This activity is supported by an educational grant from Sanofi Genzyme.

Copyright
© 2019 Med-IQ, Inc. 

Unless otherwise indicated, photographed subjects who appear within the content of this activity or on artwork associated with this activity are models; they are not actual patients or doctors.

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