Influenza on the Front Lines: Influenza Trends and Antiviral Treatment Options for Urgent Care and Emergency Medicine

Influenza on the Front Lines: Influenza Trends and Antiviral Treatment Options for Urgent Care and Emergency Medicine

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Online Course | Specialties: Emergency Medicine
Released: 11/4/2021
Expires: 11/3/2022
Max Credits: 0.75
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Joseph Toscano, MD
Clinical Content Coordinator, Urgent Care Association
Chief, Emergency Medicine and Staff Physician, San Ramon Regional Medical Center
Urgent Care Physician, John Muir Medical Group
San Ramon, CA

Christopher Chao, MD
Board of Director, College of Urgent Care Medicine
Staff Physician, WakeMed Urgent Care
WakeMed Health and Hospital
Raleigh, NC

Activity Planners
Genevieve Olucha, PhD
Clinical Content Manager
Baltimore, MD

Samantha Gordon, MS
Accreditation Manager
Baltimore, MD

Amy Sison
Director of CME
Baltimore, MD

Kathryn Schaefer, MSN, RN, CPHRM, CHCP
Associate Director, Education Quality and Compliance
East Lansing, MI

Learning Objectives
Upon completion, participants should be able to:

  • Describe strategies to aid the differential diagnosis and assessment of patients presenting with influenza-like illness
  • Compare available antivirals in terms of mechanism of action, safety, efficacy, indications, resistance, and utility for the treatment/prophylaxis of influenza
  • Integrate current guidance and emerging data surrounding available influenza antiviral agents into evidence-based, personalized treatment plans for the 2021-2022 influenza season

Target Audience
This activity is intended for clinicians in urgent care and emergency medicine practice settings.

Statement of Need
Influenza is a disease of public health concern causing significant morbidity and mortality through seasonal spread and pandemics. Certain individuals, such as the elderly, infants and very young children, and those with chronic conditions or immunosuppression, have a high risk of severe disease or complications; however, as some patients who present to urgent care centers or hospital emergency departments may not be regular patients, urgent care and emergency department clinicians may not be able to promptly identify underlying conditions that would determine risk. Diagnostic delays limit the opportunity to employ potentially critical antiviral treatments, necessary referrals, and prevention strategies, putting patients at risk of possibly life-threatening complications. The continuous evolution of the influenza virus and the emergence of resistance to traditional antiviral therapies underscores the need for additional antiviral therapies. Novel antivirals, evolving data on current and emerging treatments, and limited guidance, along with the emergence of the COVID-19 pandemic, present challenges to urgent care and emergency medicine clinicians related to optimally incorporating the latest advances into personalized influenza treatment and prevention plans.

Accreditation/Designation Statements
Med-IQ is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Med-IQ designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Med-IQ is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.

This nursing activity has been approved for up to 0.75 contact hour.

Physician assistants and other healthcare professionals who successfully complete the activity will receive a Statement of Participation indicating the maximum credits available.

Medium/Method of Participation
To receive credit, read the introductory CE material, watch the webcast, and complete the evaluation, attestation, and post-test, answering at least 70% of the post-test questions correctly.

Initial Release Date: November 4, 2021
Expiration Date: November 3, 2022
Estimated Time to Complete This Activity: 45 minutes

Disclosure Policy
Med-IQ requires any person in a position to control the content of an educational activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines "relevant financial relationships" as those in any amount occurring within the past 12 months, including those of a spouse/life partner, that could create a conflict of interest (COI). Individuals who refuse to disclose will not be permitted to contribute to this CME activity in any way. Med-IQ has policies in place that will identify and resolve COIs prior to this educational activity. Med-IQ also requires faculty to disclose discussions of investigational products or unlabeled/unapproved uses of drugs or devices regulated by the US Food and Drug Administration.

Drug/Product Usage by Faculty
Off-label/unapproved drug uses or products are mentioned within this activity.

Disclosure Statement
The content of this activity has been peer reviewed and has been approved for compliance. The faculty and contributors have indicated the following financial relationships, which have been resolved through an established COI resolution process, and have stated that these reported relationships will not have any impact on their ability to give an unbiased presentation.

Christopher Chao, MD, has indicated no real or apparent conflicts.

Joseph Toscano, MD, has indicated no real or apparent conflicts.

The peer reviewers and activity planners have no financial relationships to disclose.

Statement of Evidence-Based Content
Educational activities that assist physicians in carrying out their professional responsibilities more effectively and efficiently are consistent with the ACCME definition of continuing medical education (CME). As an ACCME-accredited provider of CME, it is the policy of Med-IQ to review and ensure that all the content and any recommendations, treatments, and manners of practicing medicine in CME activities are scientifically based, valid, and relevant to the practice of medicine. Med-IQ is responsible for validating the content of the CME activities it provides. Specifically, (1) all recommendations addressing the medical care of patients must be based on evidence that is scientifically sound and recognized as such within the profession; (2) all scientific research referred to, reported, or used in CME in support or justification of a patient care recommendation must conform to generally accepted standards of experimental design, data collection, and analysis.

Med-IQ is not liable for any decision made or action taken in reliance upon the information provided through this activity.

Contact Information
For questions or comments about this activity, please contact Med-IQ. Call (toll-free) 866 858 7434 or email

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The information provided through this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.

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Complimentary CE
This activity is available free of charge to participants.

Acknowledgment of Commercial Support
This activity is supported by an educational grant from Genentech, a member of the Roche Group.



Here are some key takeaways from this activity. Deeper insights and evidence, plus an opportunity to receive credit, are available by clicking the "Continue" button below.

  • Influenza is a major public health concern that causes substantial morbidity and mortality through seasonal spread
  • Given the unusually low activity of influenza in the US and globally during the 2020-2021 influenza season, urgent care and emergency medicine clinicians should be prepared for a potential increase in activity during the upcoming influenza season
  • Influenza can cause mild to severe disease and typically develops suddenly, with some or all of the following symptoms: fever, cough, muscle/body aches, nasal congestion, and sore throat
  • Although annual vaccination is the most effective means of influenza prevention, immunization rates are suboptimal among patients with a high risk of influenza-related complications
  • Patients who have a high risk of influenza-related complications should consider using antivirals to prevent complications
  • Four antiviral medications have been approved by the US Food and Drug Administration: baloxavir, oseltamivir, peramivir, and zanamivir; each has its own guidelines regarding safety, efficacy, resistance issues, dosing, indications, and adherence
  • Chemoprophylaxis with antiviral medication can be used to prevent influenza before or after exposure to the virus
  • If a patient has been exposed to influenza, antiviral chemoprophylaxis should be administered immediately (ideally no later than 48 hours after exposure)

View reference list.

Click "Continue" to proceed through this activity and/or receive credit. To receive credit and a certificate, you must complete all of the chapters in this activity.

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Unless otherwise indicated, photographed subjects who appear within the content of this activity or on artwork associated with this activity are models; they are not actual patients or doctors.

The information provided through this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.

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